MRI assessment of iron deposition in multiple sclerosis

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منابع مشابه

7 . MRI Assessment of Iron Deposition in Multiple Sclerosis

1Department of Neurology, Medical University of Graz, Graz, Austria, 2Department of Radiology, VU University Medical Center, Amsterdam, NL 3Neuroimaging Research Unit, Division of Neuroscience, Scientific Institute and University Hospital San Raffaele, Milan, Italy. 4Department of Radiology, Vall d’Hebron University Hospital, Barcelona, Spain. 5Department of Neurology, John Radcliffe Hospital, ...

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Correlation of MRI findings and cognitive function in multiple sclerosis patients using montreal cognitive assessment test

Background: Magnetic resonance imaging (MRI) has improved the diagnosis and management of patients with multiple sclerosis (MS). Montreal Cognitive Assessment (MoCA) is a brief, sensitive test that has been recommended by National Institute of Neurological Diseases and Stroke and Canadian Stroke Network (NINDS-CSN) as a reliable tool to detect mild cognitive impairments. This study aimed to eva...

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MRI assessment of changes in liver iron deposition post-venesection.

OBJECTIVE The aim of this study was to determine if changes in hepatic iron content in patients with hemochromatosis pre- and post-venesection could be detected by changes in liver signal intensity with MRI. MATERIALS AND METHODS The study was performed with institutional ethics approval and with informed consent. Gradient echo images were performed on 20 patients with hemochromatosis pre- an...

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Perivascular iron deposition and other vascular damage in multiple sclerosis.

Evidence of damage to cerebral vein walls was sought in 70 cases of multiple sclerosis. Seventy control cases were also examined. The multiple sclerosis cases showed venous intramural fibrinoid deposition (7%), recent haemorrhages (17%), old haemorrhages revealed by haemosiderin deposition (30%), thrombosis (6%) and thickened veins (19%). In all, 41% of all multiple sclerosis cases showed some ...

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Anomalous venous blood flow and iron deposition in multiple sclerosis.

Multiple sclerosis (MS) is primarily an autoimmune disorder of unknown origin. This review focuses iron overload and oxidative stress as surrounding cause that leads to immunomodulation in chronic MS. Iron overload has been demonstrated in MS lesions, as a feature common with other neurodegenerative disorders. However, the recent description of chronic cerebrospinal venous insufficiency (CCSVI)...

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ژورنال

عنوان ژورنال: Journal of Magnetic Resonance Imaging

سال: 2011

ISSN: 1053-1807

DOI: 10.1002/jmri.22590